Table-2.
Myocardial strain measurements in RT and control (sham-treated) rats at different ventricular levels and whole heart (global) demonstrate reduced strain post-RT.
| 8-weeks Sham- treated Controls |
8-weeks post-RT |
P value vs. control |
10-weeks post-RT |
P value vs. control |
|
|---|---|---|---|---|---|
| Circumferential-Global | −14.1±0.8 | −10.2±0.3 | 0.002 | −8.4±0.2 | < 0.001 |
| Circumferential-Base | −14.0±0.9 | −11.2±0.6 | 0.017 | −8.4±0.5 | < 0.001 |
| Circumferential-Mid | −15.0±0.7 | −10.8±0.3 | <0.001 | −9.1±0.5 | < 0.001 |
| Circumferential-Apex | −12.3±1.2 | −7.8±1.0 | 0.012 | −8.0±0.9 | 0.011 |
| Radial- Global | 23.3±1.5 | 21.7±1.5 | 0.270 | 20.9±2.0 | 0.201 |
| Radial-Base | 23.7±2.3 | 19.8±0.8 | 0.076 | 16.9±1.8 | 0.018 |
| Radial-Mid | 26.6±1.8 | 22.3±1.4 | 0.044 | 22.7±2.3 | 0.107 |
| Radial-Apex | 18.6±2.7 | 23.7±4.5 | 0.201 | 24.2±4.0 | 0.143 |
| Longitudinal - Global | −15.6±0.7 | −12.3±0.4 | 0.002 | −12.7±0.6 | 0.004 |
| Longitudinal - Base | −14.9±1.3 | −13.6±2.0 | 0.271 | −12±1.7 | 0.035 |
| Longitudinal - Mid | −16.9±0.5 | −14.3±1.3 | 0.094 | −14±1.0 | 0.059 |
| Longitudinal - Apex | −14.9±0.6 | −9.0±1.3 | 0.002 | −12±0.2 | 0.093 |
Values represent mean ± standard error of mean.