Table-3.
Myocardial displacement measurements in RT and control (sham-treated) rats at different ventricular levels and whole heart (global) demonstrate maintained, or even increased, tissue motion post-RT.
| 8-weeks Sham- treated Controls |
8-weeks post-RT |
P-value vs. control |
10-weeks post-RT |
P-value vs. control |
|
|---|---|---|---|---|---|
| Rot- Global | 14.1±1.0 | 14.4±0.7 | 0.524 | 14.7±0.7 | 0.393 |
| Rot-Base | 16.1±1.3 | 13.3±1.1 | 0.067 | 13.0±0.6 | 0.029 |
| Rot-Mid | 11.9±0.9 | 13.7±1.0 | 0.108 | 14.1±0.8 | 0.042 |
| Rot-Apex | 14.4±1.5 | 17.0±1.1 | 0.098 | 18.0±1.5 | 0.057 |
| SAX- Global | 6.1±0.4 | 6.3±0.3 | 0.444 | 6.2±0.3 | 0.559 |
| SAX-Base | 6.9±0.4 | 6.0±0.3 | 0.079 | 5.6±0.2 | 0.015 |
| SAX-Mid | 5.9±0.5 | 6.3±0.4 | 0.343 | 6.6±0.4 | 0.146 |
| SAX-Apex | 5.4±0.4 | 6.8±0.1 | 0.006 | 6.7±0.5 | 0.026 |
| LAX- Global | 5.2±0.3 | 6.0±0.7 | 0.196 | 7.0±0.5 | 0.005 |
| LAX-Base | 6.2±0.6 | 5.3±0.3 | 0.081 | 6.4±0.4 | 0.493 |
| LAX-Mid | 4.4±0.1 | 6.0±0.4 | 0.008 | 7.1±0.4 | < 0.001 |
| LAX-Apex | 5.1±0.1 | 6.7±0.2 | 0.015 | 7.4±0.1 | < 0.001 |
Myocardial rotation angle (Rot; °), short-axis motion (SAX; mm), and long-axis motion (LAX; mm) in non-irradiated control and RT rats at the base, mid-ventricular, and apical levels, and whole-heart global average (Global) value. Values represented as mean ± standard error of mean.