TABLE 2: Proposed Criteria for Consideration of Home-Based OPAT for PWID.

Optimization of treatment for SUD while hospitalized, as determined by Addiction specialists Direct collaboration between Addiction specialists and Infectious Disease specialists to ensure integrated continuity of care for the patient’s infection and substance use disorder Engagement of a longitudinal care navigator or case manager to facilitate the patient’s transition to outpatient care post discharge Safe and stable housing, ideally with engagement of live-in and/or local supports who can also help with infusions and social support Willingness of patient to engage in close follow-up with Addiction and Infectious Disease teams; this may include video tele-visits to assess integrity of PICC lines and close collaboration with visiting nurse agencies