. Author manuscript; available in PMC: 2021 Jul 23.

Published in final edited form as: Genet Med. 2021 Mar 29;23(7):1281–1287. doi: 10.1038/s41436-021-01134-9

Table 1:

Demographics of patients with HCM and single MYBPC3 VUS

	STRUM (+) n = 39 (37%)	STRUM (−) n = 66 (63%)	p-value STRUM (+) vs. STRUM (−)
Baseline Characteristics
Female, n (%)	10 (26%)	14 (21%)	0.6308
Age at diagnosis, mean (STD), year	40.31 (17.13)	41.34 (21.17)	0.9930
Follow-up time, mean (STD), year	9.82 (10.00)	12.18 (11.83)	0.7575
Maximum BMI, mean (STD) kg/m2	28.87 ( 4.10)	27.96 ( 6.03)	0.9390
lb/ft2	685.09 (97.29)	663.49 (143.09)
Race, n %			0.5107
White	35 (90%)	60 (91%)
Black	2 ( 5%)	1 ( 2%)
Other/not reported	2 ( 5%)	5 ( 8%)

Proband, n (%)	35 (90%)	64 (97%)	0.1232
Family History HCM, n (%)	13 (33%)	19 (29%)	0.6249
Family History SCD n, (%)	8 (21%)	9 (14%)	0.3553

Echocardiogram Data
Maximal LVWT, mean (STD), mm	22.73 ( 6.97)	20.83 ( 7.29)	0.4287
Minimum LVEF, mean (STD), %	59.88 ( 8.32)	60.12 (11.34)	0.9996
LVOT peak gradient > or = 30 mmHg; n (%)	9 (23%)	21 (32%)	0.3380

BMI = body mass index, LVWT = left ventricular wall thickness, LVEF = left ventricular ejection fraction, LVOT = left ventricular outflow tract