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. Author manuscript; available in PMC: 2021 Apr 30.
Published in final edited form as: HGG Adv. 2021 Jan 5;2(2):100019. doi: 10.1016/j.xhgg.2020.100019

Figure 5. High-density lipoprotein (HDL) transcriptome-wide association study (TWAS) results.

Figure 5.

Manhattan plot of the gene p values from the TWAS between HDL values and predicted gene expression. Using models trained in MESA ALL cohort, we predicted gene expression in MESA (n = 3,856) genotype data comprising individuals not used in the model training with HDL phenotype data and then carried out in TWAS. Genome-wide significance (p < 3.3 × 10−6) is shown by the red line in the plots. The x axis is ordered from chromosomes 1 to 22 (left to right).