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. Author manuscript; available in PMC: 2021 May 20.
Published in final edited form as: Nature. 2021 Apr 7;593(7857):101–107. doi: 10.1038/s41586-021-03420-7

Figure 3. Sequence and structure of the chimpanzee, orangutan, and macaque chromosome 8 centromeres.

Figure 3.

a-d) Structure and sequence identity of the a) chimpanzee H1, b) chimpanzee H2, c) orangutan, and d) macaque chromosome 8 centromeres. Each centromere has a mirrored organization consisting of 4-5 distinct evolutionary layers. The size of each centromeric region is consistent with microscopic analyses, showing increasingly bright DAPI staining with increasing centromere size. See Supplementary Figs. 10 and 11 for sequence identity heatmaps plotted on the same color scale. H1: haplotype 1; H2: haplotype 2; bar = 1 micron.