Table 1.
Histopathological scoring of joints of infected mice
| Number* of mice with each inflammation score for joints |
|||||||||
|---|---|---|---|---|---|---|---|---|---|
| Experimental groups | Knee | Tibiotarsus | |||||||
| − | +/− | + | − | +/− | + | ++ | +++ | ||
| C3H/HeJ | B. burgdorferi | 1 | 2 | 2 | 0 | 0 | 1 | 4 | 0 |
| C3H/HeN | B. burgdorferi | 2 | 1 | 2 | 0 | 0 | 3 | 1 | 1 |
| C3H/HeJ | B. burgdorferi +Bm | 1 | 0 | 4 | 0 | 0 | 0 | 3 | 2 |
| C3H/HeN | B. burgdorferi +Bm | 0 | 2 | 3 | 0 | 0 | 2 | 1 | 2 |
| C3H/HeJ | Bm | 5 | 0 | 0 | 5 | 0 | 0 | 0 | 0 |
| C3H/HeN | Bm | 2 | 2 | 0 | 4 | 0 | 0 | 0 | 0 |
*
Numbers of infected mice in each group of 5 infected mice, except 4 Bm infected C3H/HeN mice that showed a specific inflammation score for knee and tibiotarsus. Inflammation scoring was based upon infiltration of lymphocytes in the synovium and perisynovium, hyperplasia of the synovium, erosion or cellular infiltration of articular cartilage, increased synovial space and the severity of the lesions was ranked on a scale from no inflammation (−) that is equivalent to uninfected mice, to maximum inflammation (+++).