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. Author manuscript; available in PMC: 2022 Jan 15.
Published in final edited form as: Mol Psychiatry. 2020 Jul 10;26(10):5766–5788. doi: 10.1038/s41380-020-0806-5

Fig. 8. Amyloid-like pathology, staining with AmyloGlo, is shown in different lines of organoids and Human AD Brain served as positive control.

Fig. 8

a Human AD Brain (73 yrs) shows amyloid plaques in the Entorhinal cortex. b QM-DS6 (DIV100) shows no AD pathology. c–h QM-DupAPP and QM-DS1, 2, 3, 4, 5 show AmyloGlo-positive aggregates, similar to human brain. Scale bar: 20 μm. i, j Airyscan analysis of QM-DS3 showing super-resolution images of AmyloGlo-positive material with fibrillar-like appearance. Scale bar: 5 μm.