. Author manuscript; available in PMC: 2021 Dec 3.

Published in final edited form as: Heart Rhythm. 2021 May 11;18(9):1500–1507. doi: 10.1016/j.hrthm.2021.05.009

Table 4.

Heritability and correlation between traits.

	Heritability		Total P-wave duration	Standardized P-wave duration	Integral of P wave	RMSV20	RMSV30	RMSV40	RMS PW
	Simple model^*	Multivariable model⁺	Total P-wave duration	Standardized P-wave duration	Integral of P wave	RMSV20	RMSV30	RMSV40	RMS PW
Total P-wave duration	24.6%	21.6%	-	0.99±0.01	0.20±0.11	−0.41±0.13	−0.42±0.13	−0.29±0.15	−0.05±0.12
Standardized P-wave duration	20.8%	18.0%	0.93±0.00	-	0.14±0.12	−0.51±0.13	−0.57±0.12	−0.42±0.14	−0.11±0.12
Integral of P-wave	26.1%	24.9%	0.12±0.04	0.03±0.04	-	0.22±0.03	0.38±0.03	0.50±0.03	0.50±0.03
RMS20	15.0%	14.3%	−0.54±0.03	−0.52±0.03	0.34±0.15	-	0.84±0.01	0.72±0.02	0.34±0.03
RMS30	12.7%	11.9%	−0.49±0.03	−0.48±0.03	0.44±0.14	0.98±0.04	-	0.89±0.01	0.49±0.03
RMS40	12.2%	12.3%	−0.45±0.03	−0.45±0.03	0.72±0.10	0.76±0.10	0.88±0.05	-	0.60±0.02
RMS PW	24.7%	23.0%	−0.13±0.04	−0.19±0.04	0.72±0.10	0.44±0.14	0.56±0.12	0.80±0.09	-

Abbreviations: See Table 2.

Upper diagonal displays genetic correlations, and $lower diagonal shows environmental correlations$ . Values are presented as correlation coefficients ± standard error

Simple model: Adjusted for age, sex, and cohort

⁺

Multivariable model: additionally adjusted for height, weight, smoking, systolic and diastolic blood pressure, triglycerides, total/HDL cholesterol, waist, heart rate, moderate/severe alcohol consumption, diabetes, hypertension treatment, prevalent myocardial infarction, prevalent AF, prevalent heart failure, and AV node blockers.