TABLE 1.
Baseline demographic and site of delivery characteristics: Aspirin Supplementation for Pregnancy Indicated Risk Reduction In Nulliparas trial
| Variable | Total (N=11,879) | Aspirin (n=5943) | Placebo (n=5936) |
|---|---|---|---|
| Maternal age (y) | |||
| <20 | 4636 (39) | 2299 (39) | 2337 (39) |
| 20–29 | 6977 (59) | 3514 (59) | 3463 (58) |
| >29 | 266 (2) | 130 (2) | 136 (2) |
| Number of previous pregnancies not resulting in delivery | |||
| 0 | 10,780 (91) | 5412 (91) | 5368 (90) |
| 1 | 950 (8) | 466 (8) | 484 (8) |
| 2 | 149 (1) | 65 (1) | 84 (1) |
| Gestational age at enrollment (wk) | 10.1 (8.6–12.0) | 10.0 (8.6–12.0) | 10.1 (8.6–12.0) |
| Maternal education | |||
| No formal schooling | 1743 (15) | 874 (15) | 869 (15) |
| 1–6 y of schooling | 1757 (15) | 875 (15) | 882 (15) |
| 7–12 y of schooling | 7085 (60) | 3546 (60) | 3539 (60) |
| ≥13 y of schooling | 1292 (11) | 647 (11) | 645 (11) |
| Maternal height (cm) | 153.1 (7.0) | 153.1 (6.9) | 153.1 (7.0) |
| Maternal weight (kg) | 49.2 (8.9) | 49.3 (9.0) | 49.2 (8.7) |
| Maternal BMI (kg/m2) | 21.0 (3.8) | 21.0 (3.8) | 21.0 (3.7) |
| Antenatal care visits | 5 (4–6) | 5 (4–6) | 5 (4–6) |
| Delivery attendant | |||
| Physician | 5947 (50) | 2991 (50) | 2956 (50) |
| Nurse or nurse midwife | 4509 (38) | 2255 (38) | 2254 (38) |
| Traditional birth attendant | 947 (8) | 472 (8) | 475 (8) |
| Family, self, or other | 430 (4) | 208 (4) | 222 (4) |
| Delivery location | |||
| Hospital | 7077 (60) | 3535 (60) | 3542 (60) |
| Clinic or health center | 3625 (31) | 1836 (31) | 1789 (30) |
| Home or other | 1135 (10) | 557 (9) | 578 (10) |
| Delivery mode | |||
| Vaginal | 8573 (72) | 4252 (72) | 4321 (73) |
| Cesarean delivery | 2962 (25) | 1523 (26) | 1439 (24) |
| Miscarriage | 236 (2) | 112 (2) | 124 (2) |
| MTP | 66 (1) | 41 (1) | 25 (<1) |
| Site | |||
| DRC | 1361 (11) | 678 (11) | 683 (12) |
| Zambia | 1008 (8) | 502 (8) | 506 (9) |
| Guatemala | 1701 (14) | 850 (14) | 851 (14) |
| Belagavi, India | 2750 (23) | 1375 (23) | 1375 (23) |
| Pakistan | 1625 (14) | 821 (14) | 804 (14) |
| Nagpur, India | 2068 (17) | 1036 (17) | 1032 (17) |
| Kenya | 1366 (11) | 681 (11) | 685 (12) |
Data are presented as number (percentage), median (Q1–Q3), or median (standard deviation).
BMI, body mass index; DRC, Democratic Republic of the Congo; MTP, medical termination of pregnancy.
Short. Aspirin safety during pregnancy in low- and middle-income countries. Am J Obstet Gynecol Glob Rep 2021.