Table 4.
A. Vitamin B12 as a continuous variable | ||||||
---|---|---|---|---|---|---|
Case (N=1026) | Control (N=1026) | Association with maternal serum Vitamin B12 | ||||
Maternal Vitamin B12 levels (pmol/L) | Median | Median | Odds ratio (unadjusted) 95% CI | P-value | Odds ratio (adjusted*) 95% CI | P-value |
Log-transformed analysis | 4.50 | 4.52 | 0.96 (0.79–1.16) | 0.685 | 0.97 (0.79–1.18) | 0.759 |
B. As a categorical variable | ||||||
Case (N=1026) | Control (N=1026) | Association with maternal serum Vitamin B12 | ||||
Maternal Vitamin B12 (%) (pmol/L) | n (%) | n (%) | Odds ratio (unadjusted) 95% CI | P-value | Odds ratio (adjusted*) 95% CI | P-value |
Quintiles | ||||||
< 20 (< 1.20) | 202 (19.68) | 202 (19.68) | 0.96 (0.73–1.26) | 0.771 | 0.96 (0.73–1.27) | 0.803 |
20–39 (1.20–2.38) | 219 (21.34) | 205 (19.98) | 1.02 (0.77–1.34) | 0.883 | 1.03 (0.78–1.37) | 0.802 |
40–59 (2.39–4.02) | 206 (20.07) | 205 (19.98) | 0.95 (0.72–1.26) | 0.758 | 0.98 (0.74–1.29) | 0.892 |
60–79 (4.03–7.09) | 184 (17.93) | 208 (20.27) | 0.84 (0.63–1.11) | 0.236 | 0.87 (0.65–1.16) | 0.360 |
≥80 (≥7.10) | 215 (20.95) | 206 (20.07) | Reference | Reference |
Adjusted for maternal SES