Table 1:

Prioritization of Causal Risk Factors Amongst Major Lipoproteins

Peripheral Artery Disease	Marginal Inclusion Probability	Uncorrected p-value	FDR-corrected p-value
ApoB	0.856	0.003	0.015
ApoA1	0.529	0.025	0.052
HDL-C	0.467	0.031	0.052
LDL-C	0.461	0.168	0.21
Triglycerides	0.238	0.386	0.386
Coronary Artery Disease
ApoB	0.922	0.005	0.027
HDL-C	0.457	0.022	0.054
LDL-C	0.33	0.746	0.746
ApoA1	0.284	0.123	0.206
Triglycerides	0.152	0.58	0.726

Ranking of most likely causal exposures amongst major lipoproteins for peripheral artery disease and coronary artery disease prioritized using multivariable Mendelian randomization in the Mendelian randomization Bayesian Model Averaging (MR-BMA) framework. False discovery rate (FDR) corrected p-values are derived in an empirical permutation procedure. LDL-C: low-density lipoprotein cholesterol, HDL-C: high-density lipoprotein cholesterol, ApoA1: apolipoprotein A1, ApoB: apolipoprotein B.