FIGURE 1.

High-resolution MRI of paediatric and adult cadaveric human larynges at the glottis. (a) Orthogonal CE T1W gradient echo images showing orientation of the glottis in the axial, coronal and sagittal planes. The corresponding H&E-stained histological images are in the axial plane. Images are shown at a uniform scale to reflect relative specimen size. (b) CE T1W spin echo axial image showing resolution of vocal fold substructures in a 10-year-old female larynx. (c) CE T1W gradient echo and spin echo and corresponding pentachrome-stained histological images of a 13-month-old male, 10-year-old female and 74-year-old female larynx at the glottis in the axial plane. Note: The 13-month-old specimen exhibits a hyperintense signal artefact at the anterior glottis due to fluid trapped between the vocal folds during MRI; the 74-year-old specimen had the lateral TC laminae resected prior to imaging; the histological images exhibit moderate connective tissue shrinkage and tearing artefacts. AC, arytenoid cartilage; AMF, anterior macula flava; CE, contrast-enhanced; H&E, haematoxylin and eosin; IA, interarytenoid muscle; mo, month; MRI, magnetic resonance imaging; PMF, posterior macula flava; SLP, superficial lamina propria; T1W, T1-weighted; TA, thyroarytenoid muscle; TC, thyroid cartilage; VL, vocal ligament; y, year. Scale bars, 5 mm