Table 1.

Overview of the cancer GWAS datasets included in this study

Cancer types	No. of cases	No. of controls	No. of SNPs after QC^a	Reference
Breast, overall	122,977	105,974	9,934,907	Michailidou et al., 2017³⁸
Breast, ER-negative	21,468	100,564	9,942,394	Michailidou et al., 2017³⁸
Breast, ER-positive	69,501	95,042	10,267,258	Michailidou et al., 2017³⁸
Colorectal	55,168	65,160	7,910,462	Huyghe et al., 2019³⁹
Endometrial	12,906	108,979	11,595,492	O’Mara et al., 2018¹⁶
Esophageal	4,112	13,663	9,038,176	Gharahkhani et al., 2016⁴⁰
Glioma	12,488	18,169	6,931,587	Melin et al., 2017⁴¹
Head/neck	6,034	6,585	7,471,918	Lesseur et al., 2016⁴²
Lung	29,266	56,450	7,673,197	McKay et al., 2017⁴³
Melanoma	12,814	23,203	7,748,523	Law et al., 2015⁴⁴
Ovarian	22,406	40,951	9,870,154	Phelan et al., 2017⁴⁵
Pancreatic	8,638	12,217	9,568,913	Klein et al.,2018⁴⁶
Prostate	79,166	61,106	10,002,813	Schumacher et al., 2018⁴⁷
Renal	10,784	20,407	8,362,393	Scelo et al., 2017⁴⁸

Filtered out variants with imputation quality score < 0.3, minor allele frequency (MAF) < 1%, and |log odds ratio| > 3.