Table 2.
Subject demographics and biomarker for healthy controls and the four patient groups.
| HC | LA | AD | SIVD | MX | Total Patients | |
|---|---|---|---|---|---|---|
| Subjects with MRI data | 55 | 20 | 35 | 23 | 16 | 94 |
| Subjects with CSF data | 51 | 16 | 30 | 18 | 16 | 80 |
| Age μ(σ) Range | 65.7 (9.6)[50,93] | 62.8 (9)[44,82] | 69.6 (8.3)[52,84] | 67.4 (8.2)[46,83] | 75.5 (3.8)[69,83] | 68.6 (8.8)[44,84] |
| Gender (M:F) | 27:28 | 6:14 | 19:16 | 11:12 | 10:6 | 46:48 |
| WMH Volume μ(σ) | 3.3×E3(4.7×E3) | 1.4×E4(1.0×E4) | 0.7×E4(0.7×E4) | 3.8×E5(2.9×E5) | 3.2×E5(2.4×E5) | 2.04×E4(2.3×E4) |
| Log10(WMH Vol) μ(σ) | 3.22 (0.399) | 4.02(0.36) | 3.58(0.73) | 4.47(0.33) | 4.36(0.41) | 4.02(0.65) |
| PSMD μ(σ) | 0.00028(4E-05) | 0.00035(6.7E-05) | 0.00035(9.7E-05) | 0.00050(1.3E-04) | 0.00052(1.4E-04) | 0.00042(1.3E-04) |
| Aβ Ratio μ(σ) | 0.092 (0.021) | 0.089(0.022) | 0.049(0.023) | 0.074(0.028) | 0.041(0.02) | 0.061(0.03) |
| pTau μ(σ) | 54.42(12.22) | 48.7(14.34) | 94.1(38.4) | 53.3(30.4) | 96.6(58.5) | 76.2(44.2) |
| Executive function μ(σ) | 50.4(4.66) | 47.3(7.4) | 44.3(8.0) | 39.8(7.3) | 41.3(4.5) | 43.3(7.7) |
| Memory function μ(σ) | 54(8.81) | 48.1(10.2) | 30.6(10.1) | 44.8(10.3) | 32.3(9.2) | 38.1(12.6) |