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. Author manuscript; available in PMC: 2021 Aug 12.
Published in final edited form as: Free Neuropathol. 2020 Aug 4;1:10.17879/freeneuropathology-2020-2845. doi: 10.17879/freeneuropathology-2020-2845

Table 3.

Regional neuropathological comparisonsa.

Tau Control
PMC ITC P-value
% TTau 0.003 ± 0.003 0.1 ± 0.2 0.04
Tangles (/mm2) 0 ± 0 0.9 ± 2.2 0.5
  HPC
% TTau 0.002 ± 0.003 0.1 ± 0.1 0.06
Tangles (/mm2) 0 ± 0 0.4 ± 0.5 0.5
  AD
% TTau 0.9 ± 0.6 1.8 ± 0.6 0.02
Tangles (/mm2) 11.8 ± 10.2 21.9 ± 19.1 0.02
Control
% Aβ 0.1 ± 0.1 0.3 ± 0.4 0.8
Total Aβ plaques (/mm2) 3.1 ± 4.8 7.2 ± 13.4 0.9
 Fibrillar 1.6 ± 2.2 5.7 ± 11.3 0.9
 Dense-cored 1.5 ± 3.2 1.5 ± 2.4 >0.9
  HPC
% Aβ 0.3 ± 0.3 1.2 ± 0.8 0.2
Total Aβ plaques (/mm2) 4.6 ± 3.6 29 ± 23.3 0.08
 Fibrillar 2.2 ± 2.4 22.5 ± 21.9 0.1
 Dense-cored 2.2 ± 2.2 6.5 ± 4.9 0.2
  AD
% Aβ 0.7 ± 0.2 1.8 ± 0.5 0.006
Total Aβ plaques (/mm2) 13.7 ± 4.7 40.6 ± 17.7 0.001
 Fibrillar 7.7 ± 4.3 35.5 ± 17.8 0.0002
 Dense-cored 6 ± 2.8 5.1 ± 3.2 0.2
a

Mean ± standard deviation (coefficient of error).