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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Magn Reson Med. 2021 Aug 10;87(1):138–149. doi: 10.1002/mrm.28965

FIGURE 4.

FIGURE 4

A, A pulse sequence diagram of bSSFP sequence for HP 13C urea acquisition (highlighted area indicates readout duration). B, bSSFP sequence produced superior image quality (signal-to-noise ratio, resolution, sharpness) compared to the single-shot spiral GRE sequence. C, Representative simultaneously acquired metabolism and perfusion images of an adult rat: sum HP signals of each metabolite were overlaid on T2 weighted images; flip angels of lactate, alanine, pyruvate, and urea were 30°, 30°, 8°, 50°, with 2.5 × 2.5 × 21 mm spatial resolution and 4.2 s temporal resolution. D, HP signal dynamics in the aorta and kidneys of an adult rat