Table 7.
Representative1 combinations for parameters selected by LASSO regression as the most important variables in differentiating sclerotic cGVHD patients from post-HCT controls for each site.
Frequency | Relaxation Time | Stiffness | Creep | Decrement | AUC with overfit correction [95% CI] | |
---|---|---|---|---|---|---|
Abdomen L | + | + | + | + | 0.884 [0.674, 0.996] | |
Abdomen R | + | + | + | 0.902 [0.737, 0.999] | ||
Upper Arm L | + | + | 0.773 [0.431, 0.981] | |||
Upper Arm R | + | + | 0.773 [0.422, 0.983] | |||
Chest L | + | + | + | + | 0.801 [0.437, 0.992] | |
Chest R | + | 0.829 [0.546, 0.992] | ||||
Upper Back L | + | + | 0.840 [0.533, 0.994] | |||
Upper Back R | + | + | 0.756 [0.358, 0.987] | |||
Shin L | + | + | 0.855 [0.606, 0.992] | |||
Shin R | + | + | + | 0.761 [0.407, 0.978] | ||
Calf L | + | 0.741 [0.404, 0.964] | ||||
Calf R | + | + | + | + | + | 0.780 [0.411, 0.986 |
Lower Back L | + | + | + | 0.812 [0.445, 0.988] | ||
Lower Back R | + | + | + | + | 0.740 [0.327, 0.979] | |
Shoulder L | + | + | + | + | + | 0.725 [0.381, 0.955] |
Shoulder R | + | + | + | + | + | 0.757 [0.392, 0.981] |
Dorsal Forearm L | + | + | 0.782 [0.427, 0.985] | |||
Dorsal Forearm R | + | + | 0.846 [0.559, 0.995] | |||
Average across all sites | + | + | 0.871 [0.641, 0.998] | |||
Average across supine sites | + | + | 0.778 [0.429, 0.978] |
Representative: out of 10 repetitions, the most commonly selected combination of parameters for each site is shown.