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. Author manuscript; available in PMC: 2022 Oct 14.
Published in final edited form as: FASEB J. 2022 Jan;36(1):e22061. doi: 10.1096/fj.202101424R

Figure 3: Intestinal epithelial GR is required for alcohol and corticosterone-induced mucosal inflammatory response in the colon.

Figure 3:

Adult GRΔHC and GRΔIEC mice were fed a liquid diet with (EF) or without (PF) ethanol for four weeks. In some groups, animals were injected with corticosterone (Cort) daily; the other groups received the vehicle. RNA isolated from colonic mucosa was analyzed for mRNA specific for TNFα (a), IL-1β (b), IL-6 (c), and MCP1 (d) by RT-qPCR. Values are Mean ± SEM (n = 6); * = p<0.05, ** = p<0.01, *** = p<0.005, and **** = p<0.001 for significant difference between the indicated groups; “ns” = not significant.