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. Author manuscript; available in PMC: 2022 Oct 14.
Published in final edited form as: J Neuroendocrinol. 2021 Dec 5;33(12):e13063. doi: 10.1111/jne.13063

Table 1: Qualitative expression of Ar mRNA distribution by nuclei in postnatal and adult mouse brain.

−, +/−, +, ++, +++, and ++++ represent not detected, very low, low, moderate, high, and very high expression of silver grain deposits corresponding to Ar mRNA. The Allen Mouse Brain Atlas was used as a reference for names, abbreviations, and location of nuclei.

Adult Prepubertal
PND 56–70 PND 12 PND 21
Brain areas and nuclei Male Female Male Female Male Female
Cerebral Cortex
Motor (MO) +/− +/− +/− +/− +/− +/−
Olfactory nucleus (Anterior) (AON) - - ++ ++ ++ ++
Taenia tecta (TT) + +/− + + + +
Piriform (PIR) + + + + + +
Cingulate (Anterior) (ACA) + + + + + +
Endopiriform (EP) +/− +/− +/− +/− + +/−
Hippocampal Formation
Induseum griseum (IG) + + + + + +
Field CA1 (CA1) +++ +++ +++ +++ +++ +++
Field CA2 (CA2) +++ +++ +++ +++ +++ +++
Field CA3 (CA3) + + + + + +
Dentate gyrus (DG) + + +/− +/− + +
Entorhinal area (ENT) +/− +/− + + +/− +/−
Presubiculum / Subiculum (PRE/SUB) + + + + + +
Cortical subplate and cerebral nuclei
Septohippocampal nucleus (SH) + + + + + +
Lateral septal nucleus, caudodorsal (LSc) +++ + + + + +
Lateral septal nucleus, rostroventral (LSr) +++ + + + + +
Bed nucleus of stria terminalis, principal nucleus (BSTpr) ++++ +++ + + +++ +++
Cortical amygdalar area (COA) +++ +++ + + +++ +++
Medial amygdalar nucleus, posterodorsal (MEApd) +++ + + + +++ +++
Posterior amygdala (PA) +++ + +++ + +++ +
Thalamus and Subthalamus
Ventral posterior complex of the thalamus (VP) + + + + + +
Paraventricular nucleus of the thalamus (PVT) + + + + + +
Nucleus of reuniens (RE) +/− +/− + + ++ +
Subthalamic/ Parasubthalamic, caudal (STN/PSTN) ++ + + + ++ ++
Medial geniculate complex (MG) + + + + ++ +
Hypothalamus
Medial preoptic area, anterior (MPOa) + + + + + +
Medial preoptic area, posterior (MPOp) ++++ ++++ ++++ ++++ ++++ ++++
Suprachiasmatic nucleus (SCH) ++ + +/− +/− + +/−
Paraventricular hypothalamic nucleus (PVH) +/− +/− - - - -
Periventricular hypothalamic nucleus (PV) + +/− - - - -
Subparaventricular zone (SBPV) + + ++ ++ + +
Lateral hypothalamic area (LHA) +/− +/− - - - -
Arcuate hypothalamic nucleus (ARH) ++ + +/− +/− + +
Ventromedial hypothalamic nucleus, ventrolateral (VMHvl) + ++ + + ++ +
Tuberal nucleus (TU) + + - - + +
Dorsomedial nucleus of the hypothalamus (DMH) + - - - +/− -
Dorsal premammillary nucleus (PMd) + + ++ ++ ++ ++
Ventral premammillary nucleus (PMv) ++++ ++++ +++ +++ +++ +++
Supramammillary nucleus (SUM) + +/− + + + +/−
Midbrain
Periaqueductal gray, ventrolateral (PAGvl) +/− +/− +/− +/− + +
Ventral tegmental area (VTA) +/− - - - - -
Red nucleus (RN) +/− - - - +/− -
Dorsal nucleus raphe (DR) +/− +/− +/− +/− + +
Pons and Medulla
Pontine reticular nucleus (PRN) +/− +/− +/− +/− +/− +/−
Superior olivary complex (SOC) - - + + + +
Principal sensory nucleus of the trigeminal (PSV) - - + +/− + -
Parabrachial nucleus (PB) +/− +/− - - - -
Dorsal tegmental nucleus (DTN) + + + + + +
Facial motor nucleus (VII) + +/− + + + +
Cochlear nuclei (CN) +/− - + + + +
Vestibular Nucleus (VNC) +/− - + + + +
Nucleus ambiguus (AMB) +/− +/− ++ ++ ++ ++
Hypoglossal nucleus (XII) + + + + ++ ++
Nucleus of the solitary tract (NTS) +/− +/− +/− +/− +/− +/−
Dorsal motor nucleus of vagus nerve (DMX) + + + + ++ ++
Circumventricular Organs
Subfornical organ (SFO) +/− + + + +/− +/−
Area postrema (AP) +/− +/− +/− +/− + +