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. Author manuscript; available in PMC: 2010 Jun 2.
Published in final edited form as: J Neurosci. 2009 Dec 2;29(48):15223–15231. doi: 10.1523/JNEUROSCI.3252-09.2009

Figure 4. Frontal vs. temporal effects of healthy aging and Alzheimer's disease.

Figure 4

The line graphs show rate of atrophy for the frontal and the temporal regions in healthy elderly and AD patients. The regions are shown below (blue: frontal, red: temporal). In addition to the cortical areas shown, hippocampus and amygdala were included in the temporal region (yellow and cyan 3D figures). ANOVA showed a significant interaction between group and region: While the AD patients showed more atrophy in the temporal (−2.82%, SE = 0.14) than the frontal regions (−1.26%, SE = 0.11), the rate of atrophy between these two regions was comparable in the healthy controls (temporal: −0.56%, SE = 0.07/frontal: −0.38%, SE = 0.07).