Table 3.

Percentage volume change over 1 year in the AD group n.s. indicates p ≥ .01

	% change longitudinal	p<
	1 year
Volumetric ROIs
Accumbens	−2.02	10−19
Amygdala	−3.79	10−19
BrainStem	−0.65	10−16
Caudate	−1.49	10−13
Cerebellum GM	−0.99	10−25
Cerebellum WM	−0.95	10−18
Cerebral WM	−1.42	10−30
Hippocampus	−3.75	10−35
Pallidum	−0.90	10−15
Putamen	−1.45	10−22
Thalamus	−1.51	10−28
Ventricular ROIs
Lat vent	10.35	10−28
Inf lat vent	16.26	10−33
3rd ventricle	6.82	10−21
4th ventricle	1.61	.001
Surface ROIs
Cingulate, caudal ant	−1.14	10−17
Cingulate, rostral ant	−1.20	10−18
Cingulate, posterior	−1.57	10−21
Cingulate, isthmus	−1.54	10−23
Frontal, superior	−1.20	10−15
Frontal, caudal middle	−1.60	10−20
Frontal, rostral middle	−1.23	10−15
Frontal, pars opercularis	−1.31	10−18
Frontal, pars triangularis	−1.10	10−17
Frontal, pars orbitalis	−1.06	10−10
Frontal, lateral orbital	−1.47	10−18
Frontal, medial orbital	−1.19	10−17
Frontal, pole	−1.38	10−10
Parietal, precentral gyrus	−0.69	10−10
Parietal, post central gyrus	−0.27	.01
Parietal, paracentral gyrus	−0.76	10−11
Parietal, superior	−1.26	10−18
Parietal, inferior	−2.10	10−27
Parietal, supramarginal	−1.74	10−21
Parietal, precuneus	−1.61	10−24
Temporal, parahippocampal	−2.05	10−34
Temporal, entorhinal	−2.42	10−36
Temporal, pole	−2.54	10−26
Temporal, superior	−1.63	10−23
Temporal, middle	−2.87	10−31
Temporal, inferior	−2.97	10−32
Temporal, transverse	−0.59	10−6
Temporal, Banks Sup Temp Sulc	−2.53	10−28
Temporal, fusiform	−2.15	10−33
Occipital, lateral	−0.96	10−19
Occipital, pericalcarine	−0.16	n.s.
Occipital, lingual	−0.67	10−15
Occipital, cuneus	−0.50	10−9