TABLE 4.
Risk factors for 28-day mortality: multivariable logistic regression
| Lung (n = 120) |
All SOTR (n = 1081) |
|||
|---|---|---|---|---|
| Covariate | aOR ratio (95% CI) | p value | aOR ratio (95% CI) | p value |
| Age >65 years | 1.5 (0.6–4.2) | .4 | 2.0 (1.4–2.8) | <.001* |
| Lung transplant | — | — | 1.7 (1.0–2.8) | .04 |
| Single lung transplant | 2.6 (1.0–7.2) | .06 | — | — |
| Comorbidities | ||||
| Hypertension | 0.6 (0.3–1.7) | .3 | 1.3 (0.8–2.0) | .3 |
| Diabetes mellitus | 0.6 (0.2–1.7) | .3 | 1.3 (0.9–1.7) | .3 |
| Heart failure | 0.9 (0.2–7.0) | >.9 | 2.3 (1.2–3.9) | .007 |
| Obesity (BMI ≥30 kg/m2) | 2.7 (0.9–7.6) | .07 | 1.7 (1.2–2.4) | .005 |
| Chronic kidney disease | 1.0 (0.4–2.6) | >.9 | 1.1 (0.8–1.5) | .6 |
| Coronary artery disease | 0.5 (0.2–1.9) | .3 | 1.1 (0.7–1.7) | .7 |
| Chronic lung disease | — | — | 2.7 (1.5–4.6) | <.001 |
| CLAD | 3.3 (1.0–11.3) | .05* | — | — |
| Immunosuppression | ||||
| mTOR containing regimen | 0.3 (0.03–3.5) | .4 | 0.3 (1.0–0.8) | .05 |
Abbreviations: aOR, adjusted odds ratio; BMI, body mass index; CI, confidence interval; CLAD, chronic lung allograft dysfunction; mTOR, mammalian target of rapamycin; SOTR, solid organ transplant recipients.
*
Denotes statistically significant at α ≤ 0.05.