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Hyaluronic acid peptide targeting increases overall TBI-ABN activation and distribution within coronal sections of the injured hemisphere. Injured hemispheres from CCI-injured mice (representative brains from triplicate) after intravenous administration of vehicle or nanosensors with non-, moderate- or high-targeting modification (blue, nuclei; magenta, activated nanosensor; green, HApep on nanosensor; scale bar = 500 μm).
