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. Author manuscript; available in PMC: 2022 Oct 14.
Published in final edited form as: FASEB J. 2022 Feb;36(2):e22155. doi: 10.1096/fj.202100182RR

Figure 1.

Figure 1.

In human vastus lateralis, a significant association between changes in macrophage abundance and changes in (A) muscle fiber CSA (r=0.578, P <0.005, N=23), (B) MN (r=0.467, P <0.05, N=23), (C) SC (r=0.421, P <0.05, N=24), (D) CAP (r=0.507, P <0.01, N=24) following 14-weeks of PRT. (E) The change in macrophage content with PRT does not associate with the change in MMP14 expression (r=0.1190, P >0.05). N=19. (F) Absolute number of macrophages correlates to MMP14 expression at the end of PRT (r=0.578, P <0.05) N=18. Pearson r correlations were used for all analysis. CSA, cross-sectional area; MN, myonuclei; SC, satellite cells; CAP, capillaries; PRT, progressive resistance exercise training; MMP14, matrix metalloproteinase 14; FPKM, fragments per kilobase of transcript per million mapped reads.