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. Author manuscript; available in PMC: 2022 Jul 15.
Published in final edited form as: Cancer Res Commun. 2022 Jan 11;2(1):28–38. doi: 10.1158/2767-9764.CRC-21-0114

Table 5.

Primary prevention outcome measures among children of participants at baseline and post-intervention and intervention effects by the parent’s MC1R risk category.

Standard arm Precision prevention arm Intervention effecta
Outcome Baseline Post-interventionb P-valuec Baseline Post-interventionb P-valuec Beta/ Odds Ratio Type III P-value

MC1R average-risk
n = 26 n = 27
Continuous outcomesd
  Weekday hours 1.48 1.33 0.09 1.49 1.04 0.12 0.34 0.43
  Weekend hours 1.80 1.56 0.18 2.18 0.44 0.0006 −1.08 0.38
  Sun Protection Behaviors 1.44 1.21 0.82 1.51 1.68 0.48 −0.51 0.42
  Sunburns 0.53 0.53 0.13 0.54 −0.44 0.14 0.04 0.70
  Outdoor intentional tanning 1.43 0.93 0.15 1.39 1.64 0.01 0.35 0.14
Binary outcomese
   Wearing a hat often or alwaysi 0.04 0.00 -- 0.04 0.00 -- -- --
   Seeking shade or using umbrella often or alwaysf 0.16 0.37 0.21 0.30 0.46 0.33 2.27 0.70
   Wearing a shirt with sleeves often or alwaysi 0.65 1.00 -- 0.71 0.71 -- -- --
  Wearing sunglasses often or alwaysi 0.04 0.00 -- 0.07 0.08 -- -- --
  Wearing sunscreen often or alwaysi 0.31 0.20 -- 0.32 0.27 -- -- --

MC1R higher-risk
n = 31 n = 41

Continuous outcomesd
  Weekday hours 1.73 2.46 0.08 1.53 0.90 0.02 −0.94 0.005
  Weekend hoursg 1.87 2.18 0.32 1.88 0.84 0.02 −1.15 0.05
  Sun Protection behaviorsg 1.50 1.13 0.03 1.55 1.98 0.16 0.93 0.02
  Sunburns 0.29 1.21 0.13 0.20 −0.07 0.04 −0.55 0.06
  Outdoor intentional tanningg 1.24 1.35 0.41 1.22 1.06 0.23 0.12 0.34
Binary outcomese
   Wearing a hat often or alwaysi 0.06 0.08 -- 0.17 6.36 -- -- --
   Seeking shade or using umbrella often or always 0.32 0.52 0.66 0.32 0.46 0.32 1.22 0.87
   Wearing a shirt with sleeves often or alwaysf 0.61 0.62 0.86 0.68 0.69 0.96 1.06 0.94
  Wearing sunglasses often or alwaysi 0.06 0.00 -- 0.05 0.17 -- -- --
  Wearing sunscreen often or always 0.32 0.29 0.79 0.39 0.36 0.80 2.38 0.41
a

Intervention effect compares the post-intervention measure in the intervention arm to that in the standard arm, after adjusting for baseline outcome, season, predictors of missingness, and predictors of the outcome.

b

Post-intervention is the average of outcome measures obtained at the 3- and 9-month assessments.

c

Within arm p-values are from tests comparing post-intervention measures to baseline averages from a GEE model containing baseline, 3- and 9-month outcomes as the dependent variables.

d

Baseline and post-intervention values are population predicted marginal means, while the intervention effects are beta-coefficients.

e

Baseline and post-intervention values are population predicted marginal proportions, while the intervention effects are reported as odds ratios (ORs).

f

Due to sparse data, unadjusted values are presented.

g

Due to sparse data, within-arm estimates were modeled without missingness predictors.

h

Due to sparse data, all estimates were modeled without missingness predictors.

i

Due to sparse data, raw proportions are presented.