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. Author manuscript; available in PMC: 2023 Jan 6.
Published in final edited form as: Cell Mol Neurobiol. 2022 Jan 4;43(1):79–97. doi: 10.1007/s10571-021-01179-z

Table 1.

Comparison between how the timing of menopause influences the risk of CVD and glaucoma in women

% of Women in population CVD Glaucoma
54% (Garcia et al. 2016) 59% (Quigley and Broman 2006; Vajaranant and Pasquale 2012)
Stage entering menopause Directionality of change Relative risk Directionality of change Relative risk
Early menopause Higher risk 2 (Newson 2018; Wellons et al. 2012; Young and Cho 2019) Higher risk 2.5–3 (Hulsman et al. 2001; Lam et al. 2014)
Normal menopause Reference 1 Reference 1
Late menopause Lower risk 0.88 (Muka et al. 2016; Zhu et al. 2019b) Lower risk 0.5 (Pasquale et al. 2007)