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. Author manuscript; available in PMC: 2022 Feb 9.
Published in final edited form as: J Heat Transfer. 2022 Jan 18;144(3):030801. doi: 10.1115/1.4053007

Fig. 3. HIFU heating of SPIONS-laden biospecimen.

Fig. 3.

A high intensity focusing ultrasound (HIUF) system is comprised of a function generator, a gain-variable power amplifier, a transducer, a water tank, an HIFU imaging probe, and a thermal sensor. The transducer creates an ultrasound beam which is focused to a focal point in the target tissue. The kinetic energy of the ultrasound beam is converted into thermal energy, which may cause instantaneous damage to diseased cells and tissues. This heating process may be enhanced by using SPIONs delivered in the biospecimen.