Table 1. Synaptic protein composition in NL1 KO brain.
% | SEM | P-value | |
---|---|---|---|
β-catenin | 106.6754 | 7.863655 | 0.5225598 |
CamKIIα | 89.19236 | 9.984238 | 0.5153004 |
Complexin1 | 106.1328236 | 6.209750233 | 0.428415248 |
CSP | 86.68285 | 4.591786 | * 0.0326469 |
GABAα-Rα | 96.37907 | 8.532568 | 0.7916562 |
GluR1 | 103.8289703 | 8.288285636 | 0.813943664 |
Liprin | 88.46195 | 2.025309 | * 0.02345723 |
Munc-18 | 78.83607 | 2.23259 | ** 0.003578847 |
NL3 | 129.3825882 | 6.80079828 | * 0.02431589 |
NL2 | 104.98536 | 7.8880185 | 0.8019042 |
NR1 | 78.09982304 | 19.44676586 | 0.45496166 |
NR2A | 89.75655 | 8.760029 | 0.388649 |
NR2B | 93.48802144 | 6.362418868 | 0.509075447 |
NSF | 91.73566 | 7.769968 | 0.403433 |
NX-α | 82.330652 | 3.2919612 | * 0.0354927 |
NX-β | 80.442576 | 5.5239526 | * 0.0325197 |
PSD-95 | 114.2735874 | 8.599706997 | 0.240376141 |
Rab3A | 76.61192 | 8.136521 | 0.3786824 |
Rabphilin | 94.49966 | 5.816795 | 0.5273652 |
SCAMP | 106.7596 | 12.57834 | 0.7664692 |
SNAP-25 | 98.74584 | 2.942259 | 0.7681499 |
Synaptobrevin2 | 107.7806 | 7.415825 | 0.6034307 |
Synapsin1a | 118.6078871 | 5.154650933 | * 0.038798877 |
Synapsin2b | 109.4151858 | 8.029006022 | 0.440344385 |
Synaptophysin | 102.6427 | 3.131189 | 0.5091538 |
Synaptotagmin1 | 99.25104 | 1.845906 | 0.794641 |
VAchT | 121.0259 | 7.899216 | 0.2178337 |
VGAT | 102.2081 | 16.37049 | 0.9298164 |
VGlut1 | 95.76447 | 12.95471 | 0.8080348 |
Protein levels (% of wild-type) in P40 NL1 KO brain homogenate, SEM, and P-value (Student's t test) are listed (wild-type: n=4, KO: n=4).