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PROMIS Depression T-Scores in PwNID and controls during the three periods of the pandemic in 2020: first-wave (P1), trough (P2), and second-wave (P3) pandemic. Higher scores represent increasing depression. (A) Boxplot shows median/interquartile range. B) Proportion of patients with clinically significant depression, defined as PROMIS score of ≥60. Distribution of depression scores of controls (C) and PwNID (D) over time.
