Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
(A) Overall mutational signature of CH mutations. (B) Proportion of mutations attributed to signatures, which were assigned previously by Alexandrov et. al (23). Signature 3 and Signature 4 contributed most to the total mutational signature. (C) Rates of nucleotide substitution of Signature 3 and Signature 4. Data came from Alexandrov et. al (23). (D) Lung cancer patients had lower proportion of Signature 3. (E) Smoker had higher fraction of Signature 4.
