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. Author manuscript; available in PMC: 2022 Apr 27.
Published in final edited form as: Nat Genet. 2022 Mar 31;54(4):437–449. doi: 10.1038/s41588-022-01016-z

Figure 1. Manhattan plots for the additive and dominance GWAS.

Figure 1.

The top panel (green) is the additive GWAS (n = 3,037,499 individuals), and the bottom panel (red) is the dominance GWAS (n = 2,574,253 individuals). The P value and mean χ2 value are based on inflation-adjusted two-sided Z-tests. The x axis is chromosomal position, and the y axis is the significance on a −log10 scale. The dashed line marks the threshold for genome-wide significance (P = 5 × 10−8).