Fig. 5.

2,4-DAB modulates kinematics of the C startle response. A Three representative images of the peak SLC curvature in 6 days post fertilization (dpf) larvae exposed to vehicle (control, top) and to 2,4-DAB at 500 μM (bottom). B and C Bar graphs quantifying the responses latency and curvature, respectively. D and E 2D contour plot for both the latency and curvature responses at different points in the design space, including each individual cyanotoxin (BMAA, AEG, and 2,4-DAB) and their seven different mixture ratios (Linear regression model, P < 0.05). F and G Bar graphs quantify responses maximum angular velocity and duration, respectively. Levels not connected by the same letter are significantly different (Tukey–Kramer HSD, Alpha 0.05)