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Characteristics of the validation cohort.
| Characteristics | No. (%) |
|---|---|
| CRC cases | 816 |
| RNF43 mutation status | |
| Mutated | 65 (7.97) |
| Wildtype | 751 (92.03) |
| Comutations in APC, KRAS, BRAF and | 57 (88) |
| NRAS | |
| No comutation in the respective genes | 8 (12) |
| Microsatellite status | |
| MSI-H/dMMR (%) | 7 (11) |
| MSS/pMMR (%) | 42 (64) |
| Not reported (%) | 16 (25) |
