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. Author manuscript; available in PMC: 2022 Apr 13.
Published in final edited form as: FASEB J. 2022 Mar;36(3):e22192. doi: 10.1096/fj.202101298R

FIGURE 10.

FIGURE 10

KL Tg expression reduces Wnt-signaling in Pax7+ cells during early postnatal muscle growth. (A, B) Sections of Wt (A) and KL Tg+ (B) quadriceps muscle at P14 labeled with anti-Pax7 (red), anti-β-catenin (green), and DNA labeled with DAPI (blue). *Indicates Pax7+ cells also expressing active β-catenin+. Open arrowheads (>) indicate Pax7+ single-labeled cells. Bar = 10 μm. (C) Ratio of Pax7+ cells that showed activated β-catenin relative to total Pax7+ cells in Wt and KL Tg+ quadriceps muscles. *Indicates significantly different from age-matched Wt at p < .05 analyzed by t-test. Error bar represents SEM. N = 5 for each data set