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. Author manuscript; available in PMC: 2010 Mar 14.
Published in final edited form as: J Neurosci. 2010 Feb 10;30(6):2025–2038. doi: 10.1523/JNEUROSCI.4272-09.2010

Figure 8. Differential expression of CD200R on microglia, astrocytes and oligodendrocytes.

Figure 8

(A) Primary mouse microglia and astrocytes were cultured and stimulated with/without LPS or IFN-γ/TNF-α. Twenty-four hours later, cells were collected and the expression of CD200R on these cell types were examined. Flow cytometry showed that the expression levels of CD200R1 were much higher in microglia than in astrocytes under both normal and activation conditions. (B) Primary mouse microglia and oligodendrocytes were cultured and stimulated with/without LPS or TNF-α. Twenty-four hours later, cells were collected and the expression of CD200R1-R4 on these cell types were examined. RT-PCR results showed that different from microglia, oligodendrocytes did not increase CD200R1 level upon activation with LPS or TNF-α. # p < 0.05; *, p < 0.01 vs. control.