Table 2.
GWAS Results for Enamel Hypoplasia
| rsID | Chr | BP | Beta | P | A1/A2* | Nearby Gene(s)1 | |
|---|---|---|---|---|---|---|---|
| POFC | |||||||
| rs602486382 | 3 | 41883692 | −0.0600436 | 5.87E-08 | A/G | ULK4, CCK | |
| rs120439222 | 1 | 154118497 | −0.0741821 | 7.45E-08 | A/G | NUP210L, ADAR | |
| rs2414459 | 15 | 56365357 | −0.0610045 | 9.58E-08 | C/T | PYGO1 | |
| rs96161632 | 22 | 47328584 | −0.0683888 | 3.22E-07 | A/G | TBC1D22A, CELSR1 | |
| COHRA1 | |||||||
| rs245664 | 7 | 9089477 | −0.0643447 | 3.92E-08 | C/G | NXPH1 | |
| rs62522905 | 8 | 136395352 | −0.0504171 | 5.04E-08 | A/G | KHDRBS3 | |
| rs6954583 | 7 | 63292425 | 0.05167179 | 8.91E-08 | C/T | LINC01005 | |
| rs38880902 | 19 | 54317914 | −0.0647593 | 2.37E-07 | A/G | NLRP12 | |
| COHRA2 | |||||||
| rs580899132 | 4 | 79526046 | −0.1514529 | 1.57E-09 | A/G | ANXA3, BMP2K | |
| rs11232439 | 11 | 80743780 | −0.1037051 | 1.24E-08 | G/T | LOC101928944 | |
| rs57555457 | 14 | 48260934 | −0.1046353 | 1.80E-07 | C/T | MIR548Y | |
| rs62575356 | 9 | 118497768 | −0.1189798 | 2.77E-07 | C/T | LOC101928775, PAPPA | |
| rs754479 | 14 | 95331008 | −0.1108255 | 8.01E-07 | C/T | GSC | |
| Dental SCORE | |||||||
| rs2142491 | 21 | 16916381 | −0.2386754 | 6.18E-08 | C/T | USP25 | |
| rs285043633 | 4 | 94836997 | −0.2762404 | 1.94E-07 | A/G | ATOH1 | |
| rs360100812 | 1 | 212423782 | −0.2066991 | 2.67E-07 | A/C | PPP2R5A | |
| rs7780210 | 7 | 139231244 | −0.1753172 | 3.06E-07 | C/G | CLEC2L | |
| rs3010205 | 1 | 11440957 | 0.1198029 | 7.22E-07 | A/G | UBIAD1, MTOR | |
1
Gene within the+500kb window
2
These SNPs were intronic.
3
This SNP is the only one that was genotyped, the rest of SNPs in the table are imputed
*
A1 is the effect allele, A2 is the other allele