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. Author manuscript; available in PMC: 2022 Aug 3.
Published in final edited form as: J Trauma Acute Care Surg. 2022 Mar 24;93(2):137–146. doi: 10.1097/TA.0000000000003599

Figure 1.

Figure 1.

16S rRNA gene sequencing of the intestinal microbiota at baseline (“naïve”) prior to CLP+DCS demonstrates no significant difference in alpha diversity by Chao1 (A) or beta diversity by Bray-Curtis dissimilarity index (B). However, 7- and 14-days post-CLP+DCS demonstrated a significant difference in intestinal microbiota alpha diversity in male mice compared to baseline (C). While female mice also demonstrated a CLP-DCS induced microbiota shift in diversity at 7 days, this change in diversity appears restored after 14 days (D). False discovery rate (FDR), cecal ligation and puncture (CLP), daily chronic stress (DCS).