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. Author manuscript; available in PMC: 2022 May 9.
Published in final edited form as: Am J Hematol. 2022 Mar 26;97(6):E223–E225. doi: 10.1002/ajh.26542

Figure 1. mRNA-1273 vaccine-associated antibodies recognize un-complexed PF4 targets.

Figure 1.

Key testing, intervention, and platelet count trending are provided. The abscissa denotes days of hospitalization, and the ordinate shows the platelet count. Complexed PF4--PF4-polyanion ELISA (Lifecodes PF4 IgG); Un-complexed PF4-- Antibody binding to un-complexed PF4 targets in an ELISA format; PEA- PF4-dependent P-selectin Expression Assay; TPE- Therapeutic plasma exchange. Newly generated data since the prior report on this patient1 is indicated in red. Some data are reproduced with permission from Sangli et al. Thrombosis with Thrombocytopenia After the Messenger RNA-1273 vaccine. Annals of Internal Medicine. 2021 Oct;174(10):1480–1482. doi: 10.7326/L21-0244. Epub 2021 Jun 29 ©American College of Physicians.