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Amplitude of transretinal ERG a-wave as a function of flash intensity in wild type (○; n=3), Grk1−/− (□; n=3), Rpe65−/− (△; n=7), Rpe65−/−Grk1−/− (□; n=9), Rpe65−/− with 11-cis retinal (▲; n=9), and Rpe65−/−Grk1−/− with 11-cis retinal (■; n=6) retinas. The intensity-response data are fitted by equation (1). Data from Rpe65−/−Grk1−/− mice are from animals raised in cyclic-light conditions. Data are presented as means ±SEM; n=8.
