. Author manuscript; available in PMC: 2022 Oct 14.

Published in final edited form as: Glia. 2022 Apr 4;70(7):1337–1358. doi: 10.1002/glia.24177

Table 3:

Select Cytoskeletal-Related Genes altered in SMA versus Control Microglia

Gene	Log₂ Fold change	FDR - adjusted p value	Confirmed in SMA line (GM23240)
RAC2	2.46119	2.23E-09	✓
WAS	2.71399	2.18E-14	✓
ARPC1B	1.80271	2.54E-11	✓
ARPC4	1.311	2.91E-07	✓
ARPC3	1.25563	2.14E-05
EVL	2.51318	2.31E-36	✓
CORO1A	1.40784	5.47E-4	✓
PFN2	−4.733528	9.99E-30	✓
CTNNA2	−7.772883	2.32E-24	✓
WASF1	−3.935657	2.30E-47
WASF3	−4.070919	2.67E-21

Top genes differentially expressed between SMA and control microglia. A positive fold change indicates a gene whose expression is higher in the SMA microglia, and a negative fold change indicates a gene whose expression is higher in the Control Microglia.