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Hemolytic toxicity of YZ peptides
| Peptide | Estimated HC50 (μM) | Cell selectivity index 1 | HPLC retention time (min) 2 |
|---|---|---|---|
| YZ103 | >200 | NA | 8.770 |
| YZ104 | >200 | NA | 11.746 |
| YZ105 | 150 | 150 | 13.945 |
| YZ106 | 50 | 25 | 12.312 |
| YZ107 | 25 | 12.5 | 12.297 |
Defined as the ratio between MIC against S. aureus SA300 (Table 1) and HC50 of each peptide in this table.
See Supporting information for HPLC elution profiles.
