Table 1: Patient characteristics.

Normal continuous variables are reported as mean ± standard deviation while non-normal variables are reported as median with first and third quartiles (Q1 and Q3, respectively). Categorical variables are reported as number (percentage).

	“Classic ” NFHG	“Discordant” NFLG	“Paradoxical” pLFLG
	(n=27)	(n=27)	(n=27)	p-value
Clinical Characteristics
Age, years	80 ± 9	81 ± 9	82 ± 14	0.73
Gender, male	15 (56%)	13 (48%)	16 (59%)	0.71
BSA, m2	1.9 (1.7 to 2)	1.7 (1.6 to 1.9)	1.9 (1.6 to 2)	0.15
BMI, kg/m2	26 ± 5	26 ± 5	28 ± 11	0.65
Echocardiographic Characteristics
Aortic Valve area, cm2	0.87 (0.72 to 0.91)	0.8 (0.71 to 0.92)	0.74 (0.65 to 0.86)	0.13
Aortic Mean Gradient, mmHg	45 (41 to 55) †,‡	34 (28 to 37)*	31 (23 to 35)*	<0.01
LV Stroke Volume Index, mL/m2	50 ± 11†,‡	42 ± 6*,‡	30 ± 6*,†	<0.01
LV Ejection Fraction, %	69 ± 8†	64 ± 9*	64 ± 8	0.03
Mitral Regurgitation, % >Moderate	0 (0%)	0 (0%)	0 (0%)	1.0
Tricuspid Regurgitation, % >Moderate	0 (0.0%)	1 (3.7%)	2 (7.4%)	0.35
Aortic Regurgitation, % >Moderate	0 (0%)	0 (0%)	0 (0%)	1.0
PASP, mmHg	33 (26 to 43)	33 (22 to 42)	39 (31 to 48)	0.25

NFHG: normal-flow high-gradient aortic stenosis, NFLG: normal-flow low-gradient aortic stenosis, pLFLG: paradoxical low-flow low-gradient aortic stenosis

^*p<0.05 compared NFHG AS

^†p<0.05 compared to NFLG AS

^‡p<0.05 compared to pLFLG AS