FIGURE 1. ALK protein expression in primary localized prostate cancers.
A. ALK expression was assessed by immunohistochemistry using a validated antibody (clone D5F3) in two primary prostate cancer cohorts from the Johns Hopkins Hospital (N=341) and the University of Washington (N=31). B. Out of a total of 372 cases, only one tumor was positive for ALK. C. Micrographs of the ALK positive case showed cribriform morphology and expression of AR and NKX3.1, confirm the prostatic origin of this tumor.