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. Author manuscript; available in PMC: 2022 Oct 14.
Published in final edited form as: Environ Toxicol Chem. 2021 Oct 25;40(12):3226–3233. doi: 10.1002/etc.5214

FIGURE 1:

FIGURE 1:

The recognized complexity for meaningful extrapolation of toxicity knowledge across species includes both toxicokinetic and toxicodynamic considerations.