Table 2:

Effect of loss of clusterin function on IOP

	Age (Days)
n=6 (12 eyes in each)	50	70	90	105
WT IOP (mmHg) (Mean±SEM)	14.85±0.19	14.75±0.11	14.89±0.36	15.03±0.17
Clu−/− IOP (mmHg) (Mean±SEM)	16.08±0.21	16.78±0.18	18.31±0.74	18.94±0.46
Significance (p-value)	0.39	0.004	0.0001	0.0001
ΔIOP [Clu−/− - WT] (mmHg)	1.24	2.03	3.41	3.91
ΔIOP % [100*(Clu−/− IOP - WT IOP)/WT IOP]	8.35	13.76	22.9	26.01

Table shows IOP values (Mean ± SEM) of WT and CLU^−/− mice (n=6) measured at 50-, 70-, 90- and 105-days post birth. Difference in IOP is significant if p≤0.05. ΔIOP represents the change in IOP between CLU^−/− and WT, and ΔIOP% represents the percentage change in IOP in CLU^−/− compared to WT.