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Internalization of [125I]Gluc-TOCA or 125I-MAb H5 by D341 MED cells. (A) Uptake of [125I]Gluc-TOCA over time in the presence of anti-SSTR2 MAbs. Measured internalization is identical in the absence or presence of MAbs. (B) Measured uptake of 125I-MAb H5 in the presence or absence of the ligand Gluc-TOCA. Observed internalization (static and stable, as demonstrated in Fig. 7) is unchanged by the presence of ligand.
