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. Author manuscript; available in PMC: 2022 Jul 21.
Published in final edited form as: Science. 2021 Sep 23;374(6566):472–478. doi: 10.1126/science.abh2315

Fig. 3. RBD-5, −6 and −7 antibodies retain neutralization activity against pseudovirus bearing mutations singly or together in VOCs.

Fig. 3.

Fold-change differences in potency for 38 RBD-directed antibodies and an ACE2-Fc fusion (CoVIC-069) are shown in a heat map. In addition to VOCs, we also examined two pseudoviruses bearing clusters of mink-associated mutations: 4×M (G261D, Y453F, F486L and N501T) and 5×M (G261D, Y453F, F486L, N501T and V367F). Fig. S1 lists mutations represented in each variant. Fig. S10 shows neutralization curves for each virus-variant pair and Table S4 lists fold-change values corresponding to the heat map.