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. Author manuscript; available in PMC: 2022 Aug 19.
Published in final edited form as: Cancer Res. 2022 Aug 16;82(16):2838–2847. doi: 10.1158/0008-5472.CAN-22-0554

Table 1.

Tumor mutation characteristics by fluid type

Variant Statistic Tumor
n = 34
BAL cfDNA
n = 31
Plasma
n = 34
Tumor variants detected* 34 (100%) 25 (81%) 16 (47%)
Mean number of variants 5.1 1.9 0.91
Median number of variants 3.5 1.0 0.0
Mean VAF% 12.9 6.6 2.5
Median VAF% 4.2 2.4 0.09
Mean VAF%, drivers only 17.4 9.0 3.3
Median VAF%, drivers only 8.9 2.4 0.08
*

Including indels, see Supp Table 5; p < 0.05 level using a Monte-Carlo approach described in the methods.