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Study flowchart. Following the exclusion criteria, 494 patients were included in the analyses and stratified according to Barcelona Clinic Liver Cancer (BCLC) stages B and C. Statistical analysis was performed on clinical data from each group. Enhancing tumor volume (ETV) and enhancing tumor burden (ETB) cutoffs were determined, and patients were reassigned to new BCLC Bn and Cn classes according to their volumetrically quantified tumor burden. TACE = transarterial chemoembolization.
